BHD Literature Database Updated

The BHD Literature Database has been updated with a new study into the regulatory activity of folliculin.  Hong et al have presented a novel mechanism for inducing TFE3 activity, an oncogenic transcription factor also implicated in sporadic renal cell carcinomas; the authors have found that inactivation of the FLCN gene induces TFE3 activity and regulates its post-translational modification.   

To find out more download the latest version of the BHD Literature Database here.

A copy of the paper is freely available in the BHD Article Library here.

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